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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC5
All Species:
33.94
Human Site:
Y405
Identified Species:
62.22
UniProt:
Q13769
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13769
NP_001002877.1
683
78508
Y405
D
S
V
L
S
C
L
Y
P
G
D
H
G
K
K
Chimpanzee
Pan troglodytes
XP_515059
683
78517
Y405
D
S
V
L
S
C
L
Y
P
G
D
H
G
K
K
Rhesus Macaque
Macaca mulatta
XP_001106294
689
79038
Y411
D
S
V
L
S
C
L
Y
P
G
D
H
G
K
K
Dog
Lupus familis
XP_534728
683
78595
Y405
D
S
V
L
S
C
L
Y
P
G
D
H
G
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKT7
683
78667
Y405
D
S
V
L
S
C
L
Y
P
G
D
H
G
K
K
Rat
Rattus norvegicus
Q68FX7
682
78642
Y404
D
S
V
L
S
C
L
Y
P
G
D
H
G
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517072
363
40527
N98
K
K
T
P
N
P
A
N
Q
Y
Q
F
D
K
V
Chicken
Gallus gallus
Q5ZJK1
698
80563
Y420
D
S
L
L
S
C
L
Y
P
G
D
H
G
K
K
Frog
Xenopus laevis
Q7ZXA8
678
77744
Y400
D
L
I
L
G
C
L
Y
Q
G
D
D
G
K
T
Zebra Danio
Brachydanio rerio
Q6NY52
684
77815
Y406
E
S
L
L
N
C
L
Y
A
S
D
H
G
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1F4
616
70871
I351
D
L
G
N
E
L
P
I
P
G
I
Q
Y
E
L
Honey Bee
Apis mellifera
XP_396039
657
75378
G392
L
K
T
D
G
I
T
G
I
T
T
G
D
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798236
699
79519
F413
S
N
L
L
S
L
L
F
P
G
D
D
G
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.5
98
N.A.
96.1
96.1
N.A.
45.2
83.2
76.5
68.4
N.A.
25.7
37
N.A.
46.2
Protein Similarity:
100
100
96.3
99.1
N.A.
97.9
98.3
N.A.
49.7
90.9
87.1
83
N.A.
45.3
56.2
N.A.
65.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
93.3
60
53.3
N.A.
20
0
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
66.6
80
N.A.
26.6
0
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
0
8
0
0
0
0
0
0
77
16
16
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
16
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
16
0
0
8
0
77
0
8
77
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
62
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
8
8
0
8
0
0
0
0
% I
% Lys:
8
16
0
0
0
0
0
0
0
0
0
0
0
77
54
% K
% Leu:
8
16
24
77
0
16
77
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
8
16
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
0
8
8
0
70
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
16
0
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
62
0
0
62
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
16
0
0
0
8
0
0
8
8
0
0
0
8
% T
% Val:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _